Monday, August 11, 2008

132 - chronic hepatitis - types,diagnosis,antibodies,treatment

Type of hepatitis

Therapy

Chronic hepatitis B

IFN-alpha, PEG IFN-alpha, lamivudine,adefovir,entecavir

Chronic hepatitis C

PEG IFN-alpha ,ribavirin

Chronic hepatitis D

IFN-alpha, PEG IFN-alpha

Autoimmune hepatitis

Prednisone, azathioprine

Drug-associated

Withdraw drug

Cryptogenic

Prednisone?azathioprine?



Type of hepatitis

Autoantibodies

Chronic hepatitis B

uncommon

Chronic hepatitis C

Anti LKM 1

Chronic hepatitis D

Anti LKM3

Autoimmune hepatitis

ANA,anti-LKM 1, anti-SLA

Drug-associated

uncommon

Cryptogenic

none


Type of auto immune hepatitis

Antibody associated

Auto immune hepatitis type 1

Anti nuclear antibodies ( ANA )

Auto immune hepatitis type 2

Anti LKM 1 antibodies

Auto immune hepatitis type 3

Anti – SLA antibodies

Type of hepatitis

Diagnostic tests

Chronic hepatitis B

HBsAg,IgG anti-HBc,HBeAg,HBV DNA

Chronic hepatitis C

Anti-HCV,HCV RNA

Chronic hepatitis D

Anti-HDV,HDV RNA,HbsAg,IgG anti HBc

Autoimmune hepatitis

ANA(homogenous),anti-LKM1

(+-),hyperglobulinemia

Drug-associated

-------------------

Cryptogenic

All negative

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