139 - drugs causing hemolysis in G6PD deficiency

Definite hemolysis	Possible hemolysis	Doubtful hemolysis
Primaquine, dapsone / chlorproguanil	Chloroquine	Quinine
Sulfamethoxazole , dapsone	Sulfasalazine , sulfadimidine	Sulfadiazine , sulfisoxazole
Cotrimoxazole, nitrofurantoin , nalidixic acid , niridazole	Ciprofloxacin, norfloxacin	Chloramphenicol, para amino salicyclic acid
Acetanilide, phenazopyridine ( pyridium )	Aspirin greater than 3 grams per day	Aspirin lesser than 3 grams per day , acetaminophen , phenacetin
Naphthalene, methylene blue	Vitamin C greater than 1 gm, vitamin K analogues, rasburicase	Doxorubicin , probenecid

The drugs in the first row are the anti malarials causing hemolysis in glucose 6 phosphate dehydrogenase ( G6PD ) deficient individuals , the drugs in the second row are the sulfonamides causing hemolysis in glucose 6 phosphate dehydrogenase ( G6PD ) deficient individuals , the drugs in the third row are the antibiotics or antibacterials causing hemolysis in glucose 6 phosphate dehydrogenase ( G6PD ) deficient individuals , the drugs in the fourth row are the analgesics or anti pyretics causing hemolysis in glucose 6 phosphate dehydrogenase ( G6PD ) deficient individuals and the fifth row includes miscellaneous drugs and compounds causing hemolysis in glucose 6 phosphate dehydrogenase ( G6PD ) deficient individuals

138 - continuous murmur causes

2q: continuous murmur is found in ?

 

1. AS combined with AR
2. Systemic AV fistula
3. PDA with reversal of shunt
4. Aortopulmonary window
5. Rupture of sinus of valsalva

 

Answer:  b , d , e .

 

Here are the list of causes of all the conditions which causes continuous murmurs :

 

1. PDA ( patent ductus arteriosus )
2. congenital or acquired systemic arteriovenous ( AV ) fistula , coronary AV fistula
3. anomalous origin of LCA from pulmonary artery
4. ruptured sinus of valsalva aneurysm
5. coarctation of aorta
6. aortopulmonary window