901 – the highest concentration of potassium is in ?
a- plasma
b- isotonic saline
c- ringer lactate
d- darrow’s solution .
answer is d . darrow’s solution . Darrow's solution - a mixture of potassium chloride, sodium chloride and sodium lactate; used in fluid therapy to repair a potassium deficit. also called lactated potassium saline injection.
902 – highest concentration of potassium is seen in ?
a- duodenum
b- jejunum
c- ileum
d- colon
answer : d . colon .
903 - colonic pseudo-obstruction occurs in all except ?
a- diabetes mellitus
b- dermatomyositis
c- scleroderma
d- hyperthyroidism
answer is d . hyperthyroidism . pseudo-obstruction occurs in hypothyroidism not hyperthyroidism .
904 - the commonest cause of intestinal obstructions in a 30 year old indian female ?
answer : post operative adhesions .
905 - commonest site of ischemic colitis ?
a- hepatic flexure
b- splenic flexure
c- transverse colon
d- sigmoid colon
answer is b. splenic flexure .
906 - the surgery of choice for biliary atresia ?
answer : kasai's operation .
907 - the most common facial abnormality in gardener's syndrome ?
answer : multiple osteomas .
908 - turcot's syndrome is associated with ?
a- duodenal polyps
b- familial adenomatous polyposis
c- brain tumors
d- villous adenoma
e- hyperplastic polyps
answer is b and c . familial adenomatous polyposis and brain tumors .
909 - ramu is a 60 year male with carcinoma of descending colon presents with acute intestinal obstruction . in emergency department treatment of choice is ?
answer : hartman's procedure . ( for right side colon obstructive lesion - resection with ileotransverse colostomy is done ) .
910 - the most common neoplasm of the kidney ?
answer : renal cell carcinoma .
911 - colopotomy is done to treat ?
a- ischeorectal abscess
b- pelvic abscess
c- appendicular abscess
d- perianal abscess
answer is b . pelvic abscess .
912 - ursodeoxycholic acid is a ?
a- urinary stone dissolving drug
b- thrombolytic drug
c- gallstone dissolving drug
d- antifibrinolytic
answer is c . gallstone dissolving drug .
913 - aspirin sensitive asthma is associated with ?
a- extrinsic asthma
b- urticaria
c- nasal polyps
d- obesity
answer is c . nasal polyps .
914 – most common signof aspiration pneumonitis ?
a- tachypnoea
b- bronchospasm
c- cyanosis
d- crepitations
answer : a . tachypnoea .
915 – most common clinical sign of pulmonary embolism ?
answer : tachypnoea .
916 – a 60 year old man presented to the emergency with breathlessness ,facial swelling and dilated veins on the chest wall . the most common cause is ?
a- thymoma
b- lung cancer
c- hodgkin’s lymphoma
d- superior venacaval obstruction
answer : d . superior venacaval obstruction .
917 – most common cause of superior venacaval obstruction ?
a- thrombosis
b- extrinsic compression
c- mediastinal lymphoma
d- teratoma
answer is b . extrinsic compression .
918 – sleep apnoea is defined as a temporary pause in breathing during sleep lasting at least how many seconds ?
answer : 10 seconds .
919 – the following are located in the anterior mediastinum except ?
a- thymoma .
b- neurofibroma
c- neurogenic parasitic cyst
d- teratoma
answer is b. neurofibroma .
920 – X – bodies called birbeck granules are characteristically seen in ?
answer : langerhan’s cell granulomatosis .
921 – in kartagener’s syndrome all are seen except ?
a- cystic fibrosis
b- dextrocardia
c- sinusitis
d- absence of cilia
answer is a .
922 – electrical alterans is seen in ?
a- cardiac tamponade
b- restrictive cardiomyopathy
c- left atrial myxoma
d- COPD
answer is a .
923 – live vaccines should not be given with in 3 months of giving IV immunoglobulin . exception to this rule is ?
answer : OPV .
924 – vaccines with good herd immunity ?
answer : tetanus and BCG .
925 – vaccines with no herd immunity ?
answer : OPV and measles .
926 – the metabolic derangement in congenital hypertrophic pyloric stenosis ?
answer - hypochloremic alkalosis .
927 - early hematogenous seedling to tuberculous bacilli in the apex of the lungs is called?
answer : simon’s focus .
928 – crawling of an infant is at ?
answer : 9 to 10 months .
929 – the international agency supporting the no-scalpel vasectomy in
answer : UNFPA .
930 – which one of the following is not an combined injectable contraceptive ?
a- cyclofem
b- cycloprovera
c- depot provera
d- mesigyna
answer is c . depot provera .
931 – the MTP act allows the termination of pregnancy till how many weeks ?
answer : 20 weeks .
932 – the minimum number of three antenatal visits recommended by RCH programme is at ?
answer : 20 weeks , 32 weeks , 36 weeks .
933 – preterm babies are born before how many weeks of gestation ?
answer : before 37 weeks of gestation .
934 – mini pill or micro pill contains ?
a- progesterone
b- oestrogen
c- both progesterone and oestrogen
d- gossypol
e- non-steroidal and non-estrogenic components
answer is a . progesterone .
935 – the failure rate of male condom is ?
answer : 2-20 / 100 women years .
936 – the failure rate of IUCD ?
answer : 2-3 / 100 women years .
937 – the faiure rate of female condom?
Answer : 5-21 / 100 women years . ( combined type of OCPs are 100 % effective in preventing pregnancy )
938 – which one of the following is an example of a second generation IUCD ?
a- NOVA T
b- condom
c- lippes loop
d- LNG 20
e- progestasert
answer is Nova T . d and e belong to third generation IUCDs.
939 – isochromosomes – structurally abnormal chromosomes arising because of misdivision .
940 – the ESI act covers manual , supervisory , clerical and technical employees upto how many rupees per month ?
answer : 1000 per month .
941 – what is the minimum cubic feet of space for each worker prescribed under factories act ?
answer : 500 cubic feet .
942 – which one of the following method of communication is not a method of mass approach ?
a- internet
b- poster
c- role play
d- exhibition
answer is c . role play .
943 – nosocomial pneumonia is most commonly caused by ?
a- gram negative bacilli
b- gram positive bacilli
c- gram negative cocci
d- mycoplasma
answer is a . gram negative bacilli .
944 – bronchiectasis is most common in which lobe ?
answer : left lower - bronchiectasis - lobe .
945 – a drug is to be delivered by a nebuliser . the size of a droplet for its humidification is ?
answer : less than 5 microns .
946 – feature of torsades de pointes is ?
answer : prolonged QT c interval ( marked QT prolongation ) .
947 – radiofrequency ablation is done for ?
a- ventricular tachycardia
b- PSVT
c- WPW
d- atrial tachycardia
answer is c . wolf Parkinson white syndrome – radiofrequency ablation .
948 – low doses of aspirin therapy is essentially advised for all of the following conditions except ?
a- SLE
b- post myocardial infarction
c- pre eclampsia
d- IUGR
answer is a . though NSAIDs are useful no rationale , so here it is the single best answer of exclusion .
949 – a 30 year old catherine zeta jones presents with light brown lesions involving both her cheeks . the lesions had never been erythematous . which of the following is the most probable diagnosis ?
answer : chloasma .
950 – a female developed brown macule on the cheek , forehead and nose after exposure to light following delivery of the baby , the diagnosis is ?
answer : chloasma .
951 – which one of the following is not used as a tumor marker in testicular tumors ?
a- HCG
b- AFP
c- LDH
d- CEA
answer is d . CEA .
952 – hepar lobatum is due to ?
answer : syphilis . The liver in syphilitic cirrhosis, having a nodular lobulated appearance. a fissured liver, from the scars of healed syphilitic gummas.
953 – match virus with the disease ?
a- EBV - nasopharyngeal carcinoma
b- HTLV 1 - leukemia
c- HCV - Hepatocellular carcinoma
d- HPV - cervical carcinoma
answer : all are correctly matched .
954 – what is choristoma ?
answer : normal tissue in abnormal site .
955 – which of the following is not associated with malignancy ?
a- fragile x syndrome
b- fanconi’s syndrome
c- down’s syndrome
d- bloom syndrome
answer is a . fragile x syndrome is not associated with malignancy .
956 - a 2 cms firm mass is palpable beneath the skin of the left forearm in a 27 year old female. She is in excellent health . the mass is most suggestive of ?
a- metastatic carcinoma
b- mycobacterial granuloma
c- sarcoma
d- lipoma
e- staphylococcal abscess
answer is d . lipoma .
957 – cell division in malignant neoplasms , but not in normal cells , is aided by the presence of an enzyme which repairs progressive chromosomal shortening .this enzyme is known as ?
answer : topoisomerase .
958 – the most abundant glycoprotein present in the basement membrane ?
answer : laminin .
959 – triple helix structure is seen in ?
answer : collagen .
960 – of the following substances , the one that functions intracellularly in cells involved in wound healing is ?
a- fibronectin
b- laminin
c- tyrosine kinase
d- hyaluronic acid
e- collagen
answer is c . tyrosine kinase .
961 – keloid scars are made up of ?
answer : dense collagen .
962 – the appearance of red, swollen nasal mucosa from allergy to ragweed pollen has been mediated by ?
a- complement c3b
b- PAF
c- TNF
d- Histamine
e- Immunoglobulin G
Answer is d . histamine .
963 – A 50 year old male presented with epigastric pain . endoscopic biopsy reveals a tumor made up of spindle shaped cells . this is likely to be associated with ?
a- t ( 11 = 18 ) translocation
b- c KIT mutations
c- E – cadherin expression
d- ECL cell hyperplasia
Answer is a . t ( 11 = 18 ) translocation – gastric lymphoma .
Option b – c KIT mutations & PDGFR mutations – gastrointestinal stromal cell tumor .
Option c – E – cadherin expression – gastric adenocarcinoma .
Option d – ECL ( enterochromaffin like cell ) hyperplasia – gastric carcionoids .
964 – the most common outcome of pulmonary thromboembolism is ?
a- sudden death
b- corpulmonale
c- hemoptysis
d- dyspnea
e- no symptoms
answer is e . surprised ? even I am too .
965 – over several decades , which of the following inhaled pollutants is most likely to produce extensive pulmonary fibrosis ?
a- silica
b- tobacco smoke
c- ozone
d- wood dust
e- carbondioxide
answer is a . silica .
966 – in alcoholic liver disease , the following keratin filaments are seen ?
answer : Mallory bodies .
967 – the most common lysosomal storage disorder is ?
a- gaucher’s disease
b- taysach’s disease
c- wolman disease
d- niemann pick’s disease
answer is a . gaucher’s disease .
968 – C-X-C is an example of ?
answer : lipoxin .
969 – major opsonins include ?
a- Ig G antibodies
b- C3b
c- MBL – mannose binding lectin
d- All the above
Answer is d . all the above .
970 – the following are tumor suppressor genes ?
a- RB
b- BRCA 1
c- NF1
d- All the above
Answer is d . all the above .
971 – fatty change in the liver is due to the accumulation of ?
a- cholesterol
b- VLDL
c- LDL
d- Triglycerides
Answer is d . triglycerides .
972 – colonic bacteria , on digestion of dietary fibres would give ?
a- free radicals
b- glycerol
c- butyrate
d- sucrose
answer is c . butyrates .
973 – when NaCl is injected in the internal carotid artery , it causes release of ADH by acting on ?
answer : supraoptic nucleus .
974 – the dose of which of the following anti-tubercular drugs need not be adjusted in renal failure ?
a- rifampicin
b- INH
c- Ethambutol
d- Pyrazinamide
Answer is a . rifampicin . other drugs which need not be adjusted in renal failure are rifabutin and rifapentine .
975 – anti-tubercular drugs which need not be adjusted in hepatic failure ?
Answer : SREE – streptomycin , rifabutin and ethambutol .
976 – in a population of pregnant female , Hb is estimated on 100 women with standard deviation of 1 gm % . the standard error is ?
answer : standard error = standard deviation / root of number of observations . so it is 1 / root 100 = 1/10 = 0.1 . so the standard error is 0.1 .
977 – the median of values 2, 5, 7 , 10, 10, 13, 25 ?
answer is 10 . all the values are arranged in either the ascending or descending order and the centre or middle value is taken .
978 – burden of the disease is best detected by ?
answer : DALY ( disability adjusted life years ) .
979 – in ICDS the requirement in pregnant females is ?
answer : 500 cal and 25 gm protein . children less than one year – 200 cal and 8 – 10 gm protein . children ( 1 – 6 years ) – 300 cal and 15 gm protein .
980 – according to WHO criteria , anemia in infants of 6 months age is defined as Hb less than ?
answer : 110 gm/litre .
6 m to 6 years - 11 gm / dl .
6 yrs to 14 years – 12 gm/dl .
adult male – 13 gm / dl .
adult female – 12 gm/dl
adult female pregnant – 11 gm/dl .
981 – on complete hydrolysis of DNA , we will get all of the following except ?
a- adenosine
b- purine bases
c- phosphoric acid
d- deoxy pentose sugar
answer is a . adenosine will also be hydrolysed to adenine and ribose .
982 – greisinger sign is seen in ?
a- bezold abscess
b- lateral sinus thrombosis
c- acute mastoiditis
d- citelli’s abscess
answer is b . lateral sinus thrombosis .
983 – tobey ayer test Is positive in ?
answer : lateral sinus thrombosis .
984 – acoustic neuroma arises usually from ?
answer : superior vestibular nerve .
985 – McEwans triangle corresponds to ?
a- mastoid tip
b- cochlea
c- mastoid antrum
d- all the above
answer is c . mastoid antrum .
986 – dark blue tympanic membrane is seen in ?
a- cholesteatoma
b- granulation tissue
c- cholesterol granuloma
d- all the above
answer is cholesterol granuloma .
987 – common operation for meniere’s disease ?
answer : decompression of endolymphatic sac .
988 – myringoplasty is plastic repair of ?
answer : tympanic membrane .
989 – positive fistula test in the presence of intact tympanic membrane ( henneberl’s sign ) is seen in ?
answer : congenital syphilis .
990 – butterfly chart helps in finding anamolies of ?
answer : vestibular dysfunction .
991 – ototoxic drug is ?
a- gentamicin
b- kanamycin
c- metronidazole
d- pencillin
answer is b . kanamycin .
992 – otomycosis is commonly caused by ?
answer : aspergillus .
993 – earliest symptom of acoustic neuroma ?
answer : deafness .
994 – dangerous type of ear refers to ?
a- attic granulation
b- central perforation
c- marginal perforation
d- multiple perforation
answer is a . attic granulation .
995 – grommet tube is used in ?
answer : glue ear .
996 – genetic disorder of deafness developing after birth are all except ?
a- alport syndrome
b- refsum’s disease
c- cogan’s syndrome
d- usher’s syndrome
answer is d . usher’s syndrome – autosomal dominant retinitis pigmentosa with progressive sensorineural loss . congenital deafness . then how can usher’s syndrome be the answer . have to think again .
997 – structure not visualized in posterior rhinoscopy ?
a- superior turbinate
b- middle turbinate
c- inferior turbinate
d- Eustachian tube
Answer : a . superior turbinate .
998 – a 12 year old child with recurrent antrochoanal polyp . the treatment of choice is ?
answer : endoscopic nasal polypectomy .
999 – the commonest presentation of carcinoma nasopharynx ?
answer : posterior triangle lymph nodal metastasis .
1000 – Eustachian tube opens into the nasopharynx approximately 1 cm behind the ?
answer : posterior end of the inferior turbinate .
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