19 - diabetic dyslipidemia mcqs

Question 1
Which type of diabetes is associated with abnormal lipid metabolism even with good glycemic control?
Type I Diabetes mellitus
Type II Diabetes mellitus------------
Both Type I & Type II Diabetes mellitus
None

Question 2
Key features of dyslipidemia in Type II Diabetes mellitus are:
Increased small dense low-density lipoprotein cholesterol (LDL)
Increasd triglycerides
Low high-density lipoprotein cholesterol (HDL)
All of the above--------------

Question 3
Features of low-density lipoprotein cholesterol (LDL-C) in diabetes mellitus that make it more atherogenic are:
Smaller particles
More dense than in non-diabetics
Increased oxidation susceptibility
All of the above-------------

Question 4
Triglycride (TG) / High-density lipoprotein cholesterol (HDL) ratio that serves as a good predictor of small dense low-density lipoprotein cholesterol (LDL) is:
greater than are equal to 3.8------------
greater than are equal to 4.2
greater than are equal to5.6
greater than are equal to6.0

Question 5
The low-density lipoprotein cholesterol (LDL) goal in diabetic patients without coronary heart disease (CHD) is:
LDL greater than are equal to 90 mg/dl
LDL greater than are equal to 100 mg/dl-----------
LDL greater than are equal to 130 mg/dl
LDL greater than are equal to 150 mg/dl

Question 6
According to the American Diabetes association (ADA), the primary goal of therapy for diabetic patients with coronary heart disease (CHD) is low-density lipoprotein cholesterol (LDL-C) level of:
less than60mg/dl
less than70mg/dl---------
less than80mg/dl
less than90mg/dl

Question 7
High-density lipoprotein cholesterol (HDL) goal in diabetic women is:
greater than40 mg/dl
greater than50mg/dl--------------
greater than60 mg/dl
greater than70 mg/dl

Question 8
Treating elevated low-density lipoprotein cholesterol (LDL) is the first goal in diabetic dyslipidemia therapy except when triglycerides level is:
greater than 250 mg/dl
greater than 300 mg/dl
greater than 350 mg/dl
greater than 400 mg/dl----------------

Question 9
Which of these statements is true with regard to Non- High-density lipoprotein cholesterol (Non-HDL):
It is a good predictor of cardiovascular disease risk in diabetics
It is a secondary target of therapy as per ATP III guidelines
Non-HDL goal is set 30 mg/dl higher than the LDL goal
All the above-------------

Question 10
Which of these is the most effective agent in reducing low-density lipoprotein cholesterol (LDL) levels in Type II Diabetes mellitus:
Statins---------------
Fibrates
Nicotinic acid
Ezetimibe

Question 11
Which of these statements is not true with regard to combination therapy?
Statin can be combined with fibrates to treat mixed dyslipidemia
Among fibrates, fenofibrate is preffered to gemfibrozil when used as combined therapy with statin
Among fibrates, gemfibrozil is preffered to fenofibrate when used as combined therapy with statin------------
None of the above

Question 12
Which of these drugs does not adversely alter glycemic control in diabetic patients?
Fibric acid derivatives------------
Omega 3 fatty acids
Nicotinic acid
All the above

Question 13
Which of these drugs should not be given as monotherapy in patients with high triglyceride levels?
Niacin
Ezetimibe
Bile acid sequestrants-----------
Fibrates

Question 14
Fibrates are most effective in correcting:
↑ Triglyceride levels--------------
↑ Low-density lipoprotein cholesterol (LDL) levels
↓ High-density lipoprotein cholesterol (HDL) levels
↑ Very low-density lipoprotein cholesterol (VLDL) levels

Question 15
Which of these is not true with regard to ezetimibe?
Decreases absorption of cholesterol at the brush border of small intestine
Can be used in combination with statins
Metabolized to a pharmacologically active compound
Reduces absorption of fat soluble vitamins----------

Question 16
According to the ATP III guidelines, diabetic patients requiring lipid regulation should reduce intake of saturated fats to:

less than7 % of total calories---------------
less than10 % of total calories
less than15 % of total calories
less than18 % of total calories