49 - medicine mcqs - 64 to 74

64 - In the treatment of chronic hepatitis B virus:
1. Corticosteroids are always beneficial
2. 40% of patients can be expected to respond to interferon
3. Combined treatment with acyclovir and interferon is more effective than interferon alone
4. Interferon can be associated with a rise in transaminases towards the end of therapy
2 and 4 are the right answers .
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65 - Which of the following statements is / are true of streptococcus pyogenes infections:
1. They account for less than 5% of upper respiratory infections in children under the age of 2 years
2. Rheumatic chorea is a recognised sequela
3. It is a cause of erysipelas
4. The treatment of choice is ampicillin
1 , 2 , 3 are the right answers .
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66 - The following may occur in uncomplicated haemolytic jaundice:
1. Bilirubinuria
2. High conjugated serum bilirubin
3. High serum alkaline phosphatase
4. Reticulocytosis
only 4 is correct .
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67 - Nephrotoxicity is described with the following drugs:
1. Gentamicin
2. Acetazolamide
3. Ampicillin
4. Rifampicin
all are correct .
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68 - With reference to transplant immunology:
1. Hyperacute rejection is mediated by T-cells
2. Chronic rejection is immunoglobulin mediated
3. Early acute rejection is mediated by B-lymphocytes
4. Steroids are effective in reversing acute rejection of a donor organ
2 and 4 are correct .
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69 - The following are recognised associations:
1. Ulcerative colitis and HLA B8
2. Primary sclerosing cholangitis and HLA B8
3. Haemochromatosis and HLA A3
4. Primary biliary cirrhosis and HLA DR3
2 and 4 are right .
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70 - Pleural calcification is a recognised result of:
1. Tuberculosis
2. Chronic empyema
3. Asbestosis
4. Bagassosis
1 , 2 , 3 are right .
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71 - The early manifestations of chronic inorganic lead poisoning include:
1. Absent knee reflexes
2, Punctate basophilia
3. Constipation
4. Abdominal colic
2 and 4 are right .
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72 - Temporal lobe epilepsy is particularly associated with:
1. Dreamy states
2. Euphoria
3. An olfactory aura
4. Repetitive conjugate movements of the eyes
1 and 3 are right .
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73 - Myocarditis:
A may present with a functional systolic murmur
B usually causes hypertension
C causes nonspecific ST changes on ECG
D is often caused by Coxsackie virus
E is worsened by hypoxia and exercise
1. A=T, B=F, C=T, D=T, E=T.
Myocarditis may cause a systolic murmur on auscultation because of cardiac dilatation. The blood pressure in myocarditis is often normal, but if myocardial damage is severe there may be severe hypotension.
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74 - Cardiomyopathy:
A is primarily characterised by right ventricular dilatation
B is associated with thyrotoxicosis
C is usually associated with valve calcification
D secondary to alcohol has a good prognosis
E may be a cause of the sudden death syndrome
2. A=F, B=T, C=F, D=F, E=T.
Cardiomyopathy is recognised by left rather than right ventricular dilatation and systolic dysfunction in the absence of coronary artery, valvular, congenital or peripheral disease. Thus according to this definition, cardiomyopathy would not be associated with valve calcification. Cardiomyopathy is associated with thyrotoxicosis and acromegaly. Alcoholic cardiomyopathy has a poor prognosis 40-50% are dead within 3 to 6 years.
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